Implication of Testosterone in Human Puberty Attainment

Abstract This study evaluated and compared the serum levels of testosterone in male and female subjects aged 6—10 years. It also assessed the number of children among the subjects who could be potential candidates for precocious puberty based on their hormone levels. Male subjects in the study were 78 (44.1%) with a mean age of 8.3±1.4 years, height of 1.31±0.08 m, mean weight of 26.20±4.83 Kg, and Body Mass Index (BMI) of 15.30±1.71 kg/m2. Female subjects were 99 (55.9%) with a mean age of 8.55±1.37 years, height of 1.34±0.10 m, weight of 27.78±5.36 Kg, and BMI of 15.38±1.68 kg/m2. Results from statistical and clinical analyses showed that female subjects were significantly heavier and taller than male subjects (p <0.05) but the BMIs for both sexes were identical (p>0.05). Male subjects had mean testosterone of 0.49±0.38 ng/ml compared with mean testosterone of 0.57±0.59 for the female subjects. There is no significant age dependent differences in the levels of testosterone in both sexes. Based on the levels of testosterone of the children, only one of the children was adjudged qualified as candidate for precocious puberty.

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Testosterone Olufemi Ebenezer Akinluwade1,2, Alphonsus Ekpe Udoh1,2 and Kunle Joseph Akinluwade3,4,5

Author Information

1. Department of Chemical Pathology, University of Calabar Teaching Hospital (UCTH),
Calabar 540213, Nigeria.
2. Department of Medical Laboratory Science, Chemical Pathology Unit, University of Calabar, 540213, Nigeria.
3. Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut/University of Connecticut Health Center (UCHC), Farmington, CT 06032, USA.
4. Department of Materials Science and Engineering, Obafemi Awolowo University (OAU), Ile-Ife, 220282, Nigeria.
5. Department of Research and Development, Prototype Engineering Development Institute, [National Agency for Science and Engineering Infrastructure, NASENI], Ilesa, 233036, Nigeria. Journal of Advances in Biology & Biotechnology, 2394-1081,Vol.: 5, Issue.: 4 Received 9th October 2015, Accepted 8th January 2016, Published 8th February 2016

Link: http://www.sciencedomain.org/abstract/13225

by Gary Khodanian | Feb 8, 2016