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Oral contraceptive use and saliva diurnal pattern of metabolic steroid hormones in young healthy women.

Abstract BACKGROUND:
The impact of oral contraceptives (OCs) on the saliva diurnal pattern of metabolic steroid hormones remained unknown.
STUDY DESIGN:
Saliva samples were taken from young healthy women (11 OC users, 10 non-OC users) to analyze cortisol, dehydroepiandrosterone (DHEA) and testosterone 4 times (days 1, 8, 15 and 22) over one menstrual cycle.
RESULTS:
OC use decreased saliva testosterone concentrations (p<.01) under all conditions of day and time, but not saliva cortisol. OC also decreased saliva DHEA concentrations during the first part of the day (p<.05), with a dampened amplitude in its diurnal pattern.
CONCLUSION:
The clinical relevance requires further study.

DRG product(s) used in the study above

You can view the product details and buy it now

DHEA Testosterone Salivary Cortisol Vibarel-Rebot N1, Rieth N1, Lasne F2, Jaffré C3, Collomp K4.

Author Information

1 Laboratoire CIAMS, Université Paris Sud-Université Orléans, France.
2 Département des Analyses, AFLD, France.
3 Laboratoire M2S, Université Rennes 2, France.
4 Laboratoire CIAMS, Université Paris Sud-Université Orléans, France; Département des Analyses, AFLD, France. Electronic address: [email protected].
Contraception. 2015 Mar;91(3):245-7. doi: 10.1016/j.contraception.2014.11.010. Epub 2014 Nov 25.

Link: https://www.ncbi.nlm.nih.gov/pubmed/25592051

by Oleg Vishnevski | Mar 3, 2015

 
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