Description
Chagas Ab Rapid Test (Whole Blood) (RAP-5399) is an immunochromatographic test designed to detect antibodies specific for Trypanosoma cruzi in fresh blood. This protozoan is the causal agent for Trypanosomiasis or Chagas disease.
Chagas Ab Rapid Test (Whole Blood) is an immunochromatographic test capable of detecting antibodies specific for various immunologically-relevant Trypanosoma cruzi antigens. The test is based on the immunological capture of microparticles that are colored and covered with a multi-antigen protein as they pass through a membrane on which the same multi-antigen protein has been immobilized. If the sample contains antibodies against T. cruzi, they react with the RED colloid particles that are conjugated to the multi-antigen protein. The colloid particle-antibody complexes then migrate through chromatography to the reaction area. In this area, the multi-antigen protein representing T. cruzi has been
deposited on a first line; the protein captures the red particle-antibody complexes, producing a RED band. Whether the sample is negative or positive, the appearance of a BLUE
band verifies that chromatography has occurred correctly and under conditions that ensure the antigen-antibody reaction.
